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p21-Activated kinase interacts with Wnt signaling to regulate tissue polarity and gene expression

Wnt signaling is mediated by three classes of receptors, Frizzled, Ryk, and Ror. In Caenorhabditis elegans, Wnt signaling regulates the anterior/posterior polarity of the P7.p vulval lineage, and mutations in lin-17/Frizzled cause loss or reversal of P7.p lineage polarity. We found that pak-1/Pak (p...

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Detalhes bibliográficos
Main Authors: Goh, Kah Yee, Ng, Natalie Weili, Hagen, Thilo, Inoue, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465426/
https://ncbi.nlm.nih.gov/pubmed/23019370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120795109
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