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Evidence that viral RNAs have evolved for efficient, two-stage packaging

Genome packaging is an essential step in virus replication and a potential drug target. Single-stranded RNA viruses have been thought to encapsidate their genomes by gradual co-assembly with capsid subunits. In contrast, using a single molecule fluorescence assay to monitor RNA conformation and viru...

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Detalhes bibliográficos
Main Authors: Borodavka, Alexander, Tuma, Roman, Stockley, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465389/
https://ncbi.nlm.nih.gov/pubmed/23019360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204357109
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