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Identifying biologically interpretable transcription factor knockout targets by jointly analyzing the transcription factor knockout microarray and the ChIP-chip data

BACKGROUND: Transcription factor knockout microarrays (TFKMs) provide useful information about gene regulation. By using statistical methods for detecting differentially expressed genes between the gene expression microarray data of the mutant and wild type strains, the TF knockout targets of the kn...

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Autori principali: Yang, Tzu-Hsien, Wu, Wei-Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465233/
https://ncbi.nlm.nih.gov/pubmed/22898448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-102
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