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Immunoregulation in senescence: increased inducibility of antigen-specific suppressor T cells and loss of cell sensitivity to immunosuppression in aging mice.

Azobenzenearsonate (ABA)-specific T cell-mediated suppression has been studied in aging mice. ABA-specific suppressor T cells were induced in young and old mice by injection of ABA conjugated to syngeneic spleen cells (ABA-SC). These suppressor cells were tested for their ability to suppress the in...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Doria, G, Mancini, C, Adorini, L
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346516/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6212931/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.12.3803
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