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Down-regulation of the hexose transport system: metabolic basis studied with a fibroblast mutant lacking phosphoglucose isomerase.

Down-regulation ("curb") of hexose transport in Chinese hamster lung fibroblasts has been studied in a metabolic mutant highly defective in phosphoglucose isomerase (PGI; glucosephosphate isomerase; D-glucose-6-phosphate ketol-isomerase, EC 5.3.1.9). In the parental strain (PGI+) glucose as well as...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ullrey, D B, Franchi, A, Pouyssegur, J, Kalckar, H M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.12.3777
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