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Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X

The γ-carboxyglutamic acid (Gla) domain of blood coagulation factors is responsible for Ca(2+)-dependent phospholipid membrane binding. Factor X-binding protein (X-bp), an anticoagulant protein from snake venom, specifically binds to the Gla domain of factor X. The crystal structure of X-bp in compl...

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Detalhes bibliográficos
Main Authors: Mizuno, Hiroshi, Fujimoto, Zui, Atoda, Hideko, Morita, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34651/
https://ncbi.nlm.nih.gov/pubmed/11404471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131179698
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