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Use of restriction endonucleases for mapping the allele for beta s-globin.

We have reported the direct analysis of the allele for beta 2-globin by using restriction endonuclease Dde I coupled with blot-hybridization analysis. In that report we predicted that a major use of our analysis could be for the prenatal diagnosis of sickle cell anemia. Here we present such an analy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wilson, J T, Milner, P F, Summer, M E, Nallaseth, F S, Fadel, H E, Reindollar, R H, McDonough, P G, Wilson, L B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.11.3628
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