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The Bactericidal Activity of the C-type Lectin RegIIIβ against Gram-negative Bacteria involves Binding to Lipid A

RegIIIβ is a member of the C-type lectin family called RegIII. It is known to bind peptidoglycan, and its bactericidal activity shapes the interactions with commensal and pathogenic gut bacteria. However, little is known about its carbohydrate recognition specificity and the bactericidal mechanism,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miki, Tsuyoshi, Holst, Otto, Hardt, Wolf-Dietrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464586/
https://ncbi.nlm.nih.gov/pubmed/22896700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399998
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