Modulation of Conotoxin Structure and Function Is Achieved through a Multienzyme Complex in the Venom Glands of Cone Snails

The oxidative folding of large polypeptides has been investigated in detail; however, comparatively little is known about the enzyme-assisted folding of small, disulfide-containing peptide substrates. To investigate the concerted effect of multiple enzymes on the folding of small disulfide-rich pept...

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Bibliographische Detailangaben
Hauptverfasser: Safavi-Hemami, Helena, Gorasia, Dhana G., Steiner, Andrew M., Williamson, Nicholas A., Karas, John A., Gajewiak, Joanna, Olivera, Baldomero M., Bulaj, Grzegorz, Purcell, Anthony W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464536/
https://ncbi.nlm.nih.gov/pubmed/22891240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.366781
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