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Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

Dectin-1 is a pattern recognition receptor that is important for innate immune responses against fungi in humans and mice. Dectin-1 binds to β-glucans in fungal cell walls and triggers phagocytosis, production of reactive oxygen by the NADPH oxidase, and inflammatory cytokine production which all co...

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Autors principals: Ma, Jun, Becker, Courtney, Lowell, Clifford A., Underhill, David M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464523/
https://ncbi.nlm.nih.gov/pubmed/22902620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.382812
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