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Jedi-1 and MEGF10 Signal Engulfment of Apoptotic Neurons through the Tyrosine Kinase Syk

During the development of the peripheral nervous system there is extensive apoptosis, and these neuronal corpses need to be cleared to prevent an inflammatory response. Recently, Jedi-1 and MEGF10, both expressed in glial precursor cells, were identified in mouse as having an essential role in this...

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Autori principali: Scheib, Jami L., Sullivan, Chelsea S., Carter, Bruce D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464495/
https://ncbi.nlm.nih.gov/pubmed/22993420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6350-11.2012
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