Metformin in non-Diabetic Patients Presenting with ST Elevation Myocardial Infarction: Rationale and Design of the Glycometabolic Intervention as Adjunct to Primary Percutaneous Intervention in ST Elevation Myocardial Infarction (GIPS)-III Trial

BACKGROUND: Left ventricular dysfunction and the development of heart failure is a frequent and serious complication of myocardial infarction. Recent animal experimental studies suggested that metformin treatment reduces myocardial injury and preserves cardiac function in non-diabetic rats after exp...

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Hauptverfasser: Lexis, Chris P. H., van der Horst, Iwan C. C., Lipsic, Erik, van der Harst, Pim, van der Horst-Schrivers, Anouk N. A., Wolffenbuttel, Bruce H. R., de Boer, Rudolf A., van Rossum, Albert C., van Veldhuisen, Dirk J., de Smet, Bart J. G. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464381/
https://ncbi.nlm.nih.gov/pubmed/22968678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-012-6413-1
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