N-Acetylcysteine inhibits platelet–monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

AIMS/HYPOTHESIS: The aim of this study was to determine whether oral dosing with N-acetylcysteine (NAC) increases intraplatelet levels of the antioxidant, glutathione (GSH), and reduces platelet–monocyte conjugation in blood from patients with type 2 diabetes. METHODS: In this placebo-controlled ran...

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Auteurs principaux: Treweeke, A. T., Winterburn, T. J., Mackenzie, I., Barrett, F., Barr, C., Rushworth, G. F., Dransfield, I., MacRury, S. M., Megson, I. L.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464379/
https://ncbi.nlm.nih.gov/pubmed/22935960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2685-z
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