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Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen
When cells swell in hypo-osmotic solutions, chloride-selective ion channels (Cl(swell)) activate to reduce intracellular osmolality and prevent catastrophic cell rupture. Despite intensive efforts to assign a molecular identity to the mammalian Cl(swell) channel, it remains unknown. In an unbiased g...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464265/ https://ncbi.nlm.nih.gov/pubmed/23056495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046865 |
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