SIRT1 Regulates Dendritic Development in Hippocampal Neurons

Dendritic arborization is required for proper neuronal connectivity. SIRT1, a NAD+ dependent histone deacetylase, has been associated to ageing and longevity, which in neurons is linked to neuronal differentiation and neuroprotection. In the present study, the role of SIRT1 in dendritic development...

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Bibliografiske detaljer
Main Authors: Codocedo, Juan F., Allard, Claudio, Godoy, Juan A., Varela-Nallar, Lorena, Inestrosa, Nibaldo C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464248/
https://ncbi.nlm.nih.gov/pubmed/23056585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047073
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