Angiopoietin-Like 4 Mediates PPAR Delta Effect on Lipoprotein Lipase-Dependent Fatty Acid Uptake but Not on Beta-Oxidation in Myotubes

Peroxisome proliferator-activated receptor (PPAR) delta is an important regulator of fatty acid (FA) metabolism. Angiopoietin-like 4 (Angptl4), a multifunctional protein, is one of the major targets of PPAR delta in skeletal muscle cells. Here we investigated the regulation of Angptl4 and its role i...

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Main Authors: Robciuc, Marius R., Skrobuk, Paulina, Anisimov, Andrey, Olkkonen, Vesa M., Alitalo, Kari, Eckel, Robert H., Koistinen, Heikki A., Jauhiainen, Matti, Ehnholm, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464237/
https://ncbi.nlm.nih.gov/pubmed/23056264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046212
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