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Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1
BACKGROUND: The mechanism by which HIV-1 induces AIDS is still unknown. Previously, synthetic peptides corresponding to the conserved immunosuppressive (isu) domain in gp41 of HIV-1 had been shown to inhibit proliferation and to modulate cytokine expression of immune cells. The question is, whether...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464125/ https://ncbi.nlm.nih.gov/pubmed/22889273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-67 |
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