Bioconjugation of recombinant tissue plasminogen activator to magnetic nanocarriers for targeted thrombolysis

Low-toxicity magnetic nanocarriers (MNCs) composed of a shell of poly [aniline-co-N-(1-one-butyric acid) aniline] over a Fe(3)O(4) magnetic nanoparticle core were developed to carry recombinant tissue plasminogen activator (rtPA) in MNC-rtPA for targeted thrombolysis. With an average diameter of 14....

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Detalhes bibliográficos
Main Authors: Yang, Hung-Wei, Hua, Mu-Yi, Lin, Kun-Ju, Wey, Shiaw-Pyng, Tsai, Rung-Ywan, Wu, Siao-Yun, Lu, Yi-Ching, Liu, Hao-Li, Wu, Tony, Ma, Yunn-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464084/
https://ncbi.nlm.nih.gov/pubmed/23055728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32939
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