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Antagonism of Metabotropic Glutamate 1 Receptors Attenuates Behavioral Effects of Cocaine and Methamphetamine in Squirrel Monkeys

Within the group I family of metabotropic glutamate receptors (mGluRs), substantial evidence points to a role for mGluR5 mechanisms in cocaine's abuse-related behavioral effects, but less is understood about the contribution of mGluR1, which also belongs to the group I mGluR family. The selecti...

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Main Authors: Achat-Mendes, Cindy, Platt, Donna M., Spealman, Roger D.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464036/
https://ncbi.nlm.nih.gov/pubmed/22815535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.196295
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