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Mechanisms of Cadmium-Induced Proximal Tubule Injury: New Insights with Implications for Biomonitoring and Therapeutic Interventions

Cadmium is an important industrial agent and environmental pollutant that is a major cause of kidney disease. With chronic exposure, cadmium accumulates in the epithelial cells of the proximal tubule, resulting in a generalized reabsorptive dysfunction characterized by polyuria and low-molecular-wei...

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Autores principales: Prozialeck, Walter C., Edwards, Joshua R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464032/
https://ncbi.nlm.nih.gov/pubmed/22669569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.166769
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