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Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation

Endogenous stem cell recruitment to the site of skeletal injury is key to enhanced osseous remodeling and neovascularization. To this end, this study utilized a novel bone allograft coating of poly(lactic-co-glycolic acid) (PLAGA) to sustain the release of FTY720, a selective agonist for sphingosine...

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Hlavní autoři: Huang, Cynthia, Das, Anusuya, Barker, Daniel, Tholpady, Sunil, Wang, Tiffany, Cui, Quanjun, Ogle, Roy, Botchwey, Edward
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464023/
https://ncbi.nlm.nih.gov/pubmed/21863314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-011-1217-3
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