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Allelic and nonallelic homology of a supergene family.

A model to explain the high degree of polymorphism at the major histocompatibility complex (MHC) is described. The model incorporates domain transfer between the different loci in a supergene family by either gene conversion or double unequal crossing-over. Population genetics theory is used to form...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Ohta, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346393/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3251
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