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Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation

Increased intracranial pressure (ICP) associated with traumatic brain injury (TBI) is linked to increased morbidity. Although our understanding of the pathobiology of TBI has expanded, questions remain regarding the specific neuronal somatic and axonal damaging consequences of elevated ICP, independ...

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Detalhes bibliográficos
Main Authors: Lafrenaye, Audrey D, McGinn, Melissa J, Povlishock, John T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463883/
https://ncbi.nlm.nih.gov/pubmed/22781336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.95
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