A Randomized, Double-Blind Study of Larazotide Acetate to Prevent the Activation of Celiac Disease During Gluten Challenge

OBJECTIVES: In patients with celiac disease, enteropathy is caused by the entry of gluten peptides into the lamina propria of the intestine, in which their immunogenicity is potentiated by tissue transglutaminase (tTG) and T-helper type 1–mediated immune responses are triggered. Tight junction disas...

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Autors principals: Leffler, Daniel A, Kelly, C P, Abdallah, H Z, Colatrella, A M, Harris, L A, Leon, F, Arterburn, L A, Paterson, B M, Lan, Z H, Murray, J A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Colon/Small Bowel
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463856/
https://ncbi.nlm.nih.gov/pubmed/22825365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2012.211
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