In vivo SELEX reveals novel sequence and structural determinants of Nrd1-Nab3-Sen1-dependent transcription termination

The Nrd1-Nab3-Sen1 (NNS) complex pathway is responsible for transcription termination of cryptic unstable transcripts and sn/snoRNAs. The NNS complex recognizes short motifs on the nascent RNA, but the presence of these sequences alone is not sufficient to define a functional terminator. We generate...

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Main Authors: Porrua, Odil, Hobor, Fruzsina, Boulay, Jocelyne, Kubicek, Karel, D'Aubenton-Carafa, Yves, Gudipati, Rajani Kanth, Stefl, Richard, Libri, Domenico
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463846/
https://ncbi.nlm.nih.gov/pubmed/23032188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.237
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