Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

Ciguatoxins are sodium channel activator toxins that cause ciguatera, the most common form of ichthyosarcotoxism, which presents with peripheral sensory disturbances, including the pathognomonic symptom of cold allodynia which is characterized by intense stabbing and burning pain in response to mild...

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Main Authors: Vetter, Irina, Touska, Filip, Hess, Andreas, Hinsbey, Rachel, Sattler, Simon, Lampert, Angelika, Sergejeva, Marina, Sharov, Anastasia, Collins, Lindon S, Eberhardt, Mirjam, Engel, Matthias, Cabot, Peter J, Wood, John N, Vlachová, Viktorie, Reeh, Peter W, Lewis, Richard J, Zimmermann, Katharina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463840/
https://ncbi.nlm.nih.gov/pubmed/22850668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.207
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