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Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes

As antibody-based diagnosis and therapy grow at an increased pace, there is a need for methods which rapidly and accurately determine antibody-antigen interactions. Here, we report a method for the multiplex determination of antibody epitopes using bacterial cell-surface display. A protein-fragment...

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Autors principals: Hudson, Elton P., Uhlen, Mathias, Rockberg, Johan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463815/
https://ncbi.nlm.nih.gov/pubmed/23050090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00706
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