Protective Antioxidant and Antiapoptotic Effects of ZnCl(2) in Rat Pancreatic Islets Cultured in Low and High Glucose Concentrations

AIM/HYPOTHESIS: Rat pancreatic islet cell apoptosis is minimal after prolonged culture in 10 mmol/l glucose (G10), largely increased in 5 mmol/l glucose (G5) and moderately increased in 30 mmol/l glucose (G30). This glucose-dependent asymmetric V-shaped profile is preceded by parallel changes in the...

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Main Authors: Duprez, Jessica, Roma, Leticia P., Close, Anne-Françoise, Jonas, Jean-Christophe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463538/
https://ncbi.nlm.nih.gov/pubmed/23056475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046831
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