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Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a

Using the zebrafish model we describe a previously unrecognized requirement for the transcription factor gata4 controlling embryonic angiogenesis. The development of a vascular plexus in the embryonic tail, the caudal hematopoietic tissue (CHT), fails in embryos depleted of gata4. Rather than formin...

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Detalhes bibliográficos
Main Authors: Torregroza, Ingrid, Holtzinger, Audrey, Mendelson, Karen, Liu, Ting-Chun, Hla, Timothy, Evans, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463525/
https://ncbi.nlm.nih.gov/pubmed/23056483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046844
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