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Hydrogels containing redispersible spray-dried melatonin-loaded nanocapsules: a formulation for transdermal-controlled delivery

The aim of the present study was to develop a transdermal system for controlled delivery of melatonin combining three strategies: nanoencapsulation of melatonin, drying of melatonin-loaded nanocapsules, and incorporation of nanocapsules in a hydrophilic gel. Nanocapsules were prepared by interfacial...

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Bibliographic Details
Main Authors: Hoffmeister, Cristiane RD, Durli, Taís L, Schaffazick, Scheila R, Raffin, Renata P, Bender, Eduardo A, Beck, Ruy CR, Pohlmann, Adriana R, Guterres, Sílvia S
Format: Artigo
Language:Inglês
Published: Springer 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463463/
https://ncbi.nlm.nih.gov/pubmed/22587614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-7-251
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