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Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man.

We tested the hypothesis that the rate of cholesterol synthesis in tissues determines the concentrations of mevalonic acid (MVA) in plasma. We found that plasma MVA concentrations were correlated (i) with increased rates of whole-body cholesterol synthesis (measured by sterol-balance methods) in pat...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Parker, T S, McNamara, D J, Brown, C, Garrigan, O, Kolb, R, Batwin, H, Ahrens, E H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346344/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6953446/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.3037
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