The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution

Paralogs NDE1 (nuclear distribution element 1) and NDEL1 (NDE-like 1) are essential for mitosis and neurodevelopment. Both proteins are predicted to have similar structures, based upon high sequence similarity, and they co-complex in mammalian cells. X-ray diffraction studies and homology modeling s...

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Autori principali: Soares, Dinesh C., Bradshaw, Nicholas J., Zou, Juan, Kennaway, Christopher K., Hamilton, Russell S., Chen, Zhuo A., Wear, Martin A., Blackburn, Elizabeth A., Bramham, Janice, Böttcher, Bettina, Millar, J. Kirsty, Barlow, Paul N., Walkinshaw, Malcolm D., Rappsilber, Juri, Porteous, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463352/
https://ncbi.nlm.nih.gov/pubmed/22843697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393439
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