Identification and Characterization of d-Hydroxyproline Dehydrogenase and Δ(1)-Pyrroline-4-hydroxy-2-carboxylate Deaminase Involved in Novel l-Hydroxyproline Metabolism of Bacteria: METABOLIC CONVERGENT EVOLUTION

l-Hydroxyproline (4-hydroxyproline) mainly exists in collagen, and most bacteria cannot metabolize this hydroxyamino acid. Pseudomonas putida and Pseudomonas aeruginosa convert l-hydroxyproline to α-ketoglutarate via four hypothetical enzymatic steps different from known mammalian pathways, but the...

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Detalhes bibliográficos
Main Authors: Watanabe, Seiya, Morimoto, Daichi, Fukumori, Fumiyasu, Shinomiya, Hiroto, Nishiwaki, Hisashi, Kawano-Kawada, Miyuki, Sasai, Yuuki, Tozawa, Yuzuru, Watanabe, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463351/
https://ncbi.nlm.nih.gov/pubmed/22833679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374272
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