Porphyromonas gingivalis Mediates Inflammasome Repression in Polymicrobial Cultures through a Novel Mechanism Involving Reduced Endocytosis

The interleukin (IL)-1β-processing inflammasome has recently been identified as a target for pathogenic evasion of the inflammatory response by a number of bacteria and viruses. We postulated that the periodontal pathogen, Porphyromonas gingivalis may suppress the inflammasome as a mechanism for its...

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Main Authors: Taxman, Debra J., Swanson, Karen V., Broglie, Peter M., Wen, Haitao, Holley-Guthrie, Elizabeth, Huang, Max Tze-Han, Callaway, Justin B., Eitas, Tim K., Duncan, Joseph A., Ting, Jenny P. Y.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
主題:
Microbiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463344/
https://ncbi.nlm.nih.gov/pubmed/22843689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401737
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