Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

The SIN3A-HDAC complex deacetylates histones thereby repressing gene transcription. Here we describe family with sequence similarity 60A (FAM60A), a cell cycle-regulated protein that binds to the SIN3-HDAC complex. FAM60A expression peaks during G(1) and S phases of the cell cycle in U2OS cells, in...

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Bibliografiske detaljer
Main Authors: Muñoz, Ivan M., MacArtney, Thomas, Sanchez-Pulido, Luis, Ponting, Chris P., Rocha, Sonia, Rouse, John
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463326/
https://ncbi.nlm.nih.gov/pubmed/22865885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.382499
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