Nifetepimine, a Dihydropyrimidone, Ensures CD4(+) T Cell Survival in a Tumor Microenvironment by Maneuvering Sarco(endo)plasmic Reticulum Ca(2+) ATPase (SERCA)

Multiple mechanisms have been proposed by which tumors induce T cell apoptosis to circumvent tumor immune-surveillance. Although sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) have long been known to regulate intracellular Ca(2+) homeostasis, few studies have examined the role of SERCA in process...

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Autori principali: Ghosh, Swatilekha, Adhikary, Arghya, Chakraborty, Samik, Nandi, Pinki, Mohanty, Suchismita, Chakraborty, Supriya, Bhattacharjee, Pushpak, Mukherjee, Sanhita, Putatunda, Salil, Chakraborty, Srabasti, Chakraborty, Arijit, Sa, Gaurisankar, Das, Tanya, Sen, Parimal C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463307/
https://ncbi.nlm.nih.gov/pubmed/22851172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.357889
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