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Eukaryotic N-Glycosylation Occurs via the Membrane-anchored C-terminal Domain of the Stt3p Subunit of Oligosaccharyltransferase

N-Glycosylation is an essential and highly conserved protein modification. In eukaryotes, it is catalyzed by a multisubunit membrane-associated enzyme, oligosaccharyltransferase (OT). We report the high resolution structure of the C-terminal domain of eukaryotic Stt3p. Unlike its soluble β-sheet-ric...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Chengdong, Bhaskaran, Rajagopalan, Mohanty, Smita
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463301/
https://ncbi.nlm.nih.gov/pubmed/22865878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.342253
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