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Activation of purified soluble guanylate cyclase by protoporphyrin IX.

Soluble guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] purified from bovine lung is markedly activated (30- to 40-fold) by protoporphyrin IX (Ka, 15-25 nM) and is inhibited by hematin (Ki, 3.7 microM) when MgGTP is used as substrate. Guanylate cyclase possesses specific activiti...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Ignarro, L J, Wood, K S, Wolin, M S
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1982
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346308/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6123998/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.2870
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