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Length Bias Correction in Gene Ontology Enrichment Analysis Using Logistic Regression
When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called “length bias”, will influence subsequent analyses such as Gene Ontology enr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462807/ https://ncbi.nlm.nih.gov/pubmed/23056249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046128 |
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