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Length Bias Correction in Gene Ontology Enrichment Analysis Using Logistic Regression

When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called “length bias”, will influence subsequent analyses such as Gene Ontology enr...

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Bibliografiske detaljer
Main Authors: Mi, Gu, Di, Yanming, Emerson, Sarah, Cumbie, Jason S., Chang, Jeff H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462807/
https://ncbi.nlm.nih.gov/pubmed/23056249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046128
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