Reconstitution of a variant macrophage cell line defective in oxygen metabolism with a H2O2-generating system.

A variant clone, C3C, derived from the cloned macrophage cell line J774.16 lacks the capacity to produce O2- or H2O2 after appropriate stimulation. When the parental and variant cell lines were infected with epimastigotes of Trypanosoma cruzi, the parasites were killed or their growth was inhibited...

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Bibliographic Details
Main Authors: Tanaka, Y, Kiyotaki, C, Tanowitz, H, Bloom, B R
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC346244/
https://ncbi.nlm.nih.gov/pubmed/7045866
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