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Engineering of Therapeutic Polypeptides Through Chemical Synthesis: Early Lessons From Human Parathyroid Hormone and Analogs

Application of chemical synthesis to gain access to high purity hPTH as well as more stable analogs was accomplished through a menu of extended NCL followed by metal free dethiylation.

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Dades bibliogràfiques
Autors principals: Dong, Suwei, Shang, Shiying, Li, Jianfeng, Tan, Zhongping, Dean, Thomas, Maeda, Akira, Gardella, Thomas J., Danishefsky, Samuel J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462362/
https://ncbi.nlm.nih.gov/pubmed/22891619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja306637u
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