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A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites

Long-lasting forms of activity-dependent synaptic plasticity involve molecular modifications that require gene expression. Here, we describe a cellular mechanism that mediates the targeting newly synthesized gene transcripts to individual synapses where they are locally translated. The features of t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Steward, Oswald, Worley, Paul F.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34623/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416188/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131146398
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