The persistence of atopic dermatitis and Filaggrin mutations in a US longitudinal cohort

BACKGROUND: Atopic dermatitis (AD) is a common skin disease that is characterized by recurrent episodes of itching. Filaggrin loss-of-function mutations (FLG null) have been associated with an increased risk of developing AD. OBJECTIVE: To evaluate the effect of individual FLG null mutations on the...

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Autori principali: Margolis, David J., Apter, Andrea J., Gupta, Jayanta, Hoffstad, Ole, Papadopoulos, Maryte, Campbell, Linda E., Sandilands, Aileen, McLean, WH Irwin, Rebbeck, Tim R., Mitra, Nandita
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462287/
https://ncbi.nlm.nih.gov/pubmed/22951058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.07.008
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