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Cocaine and phencyclidine inhibition of the acetylcholine receptor: analysis of the mechanisms of action based on measurements of ion flux in the millisecond-to-minute time region.

The effects of cocaine and of phencyclidine and procaine on acetylcholine receptor-controlled ion flux were measured in the millisecond-to-minute time region. Chemical kinetic measurements of ion flux were made in membrane vesicles prepared from the electric organ of Electrophorus electricus and in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Karpen, J W, Aoshima, H, Abood, L G, Hess, G P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6953408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.8.2509
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