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Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes

OBJECTIVE: Naturally-arising IgM antibodies (NAbs) to apoptotic cell (AC) determinants are present from birth and can be further induced by AC challenge. In systemic lupus erythematosus, lower anti-AC NAb levels have been associated with higher disease activity. We have recently shown that a prototy...

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Autors principals: Vas, Jaya, Grönwall, Caroline, Marshak-Rothstein, Ann, Silverman, Gregg J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462267/
https://ncbi.nlm.nih.gov/pubmed/22577035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34537
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