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Methylation Alterations of WT1 and Homeobox Genes in Inflamed Muscle Biopsies from Untreated Juvenile Dermatomyositis Suggests Self-renewal Capacity

OBJECTIVE: To determine the impact of methylation alteration in inflamed muscles from children with Juvenile Dermatomyositis (JDM) and other Idiopathic Inflammatory Myopathies (IIM). METHODS: MRI-directed diagnostic muscle biopsies (MBx) from 20 JDM children and 4 healthy controls were used for geno...

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Detalhes bibliográficos
Main Authors: Wang, Min, Xie, Hehuang, Shrestha, Sheela, Sredni, Simone, Morgan, Gabrielle A., Pachman, Lauren M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462248/
https://ncbi.nlm.nih.gov/pubmed/22674142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34573
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