The Critical Role of Astragalus Polysaccharides for the Improvement of PPRAα-Mediated Lipotoxicity in Diabetic Cardiomyopathy

BACKGROUND: Obesity-related diabetes mellitus leads to increased myocardial uptake and oxidation of fatty acids, resulting in a form of cardiac dysfunction referred to as lipotoxic cardiomyopathy. We have shown previously that Astragalus polysaccharides (APS) administration was sufficient to improve...

Full description

Saved in:
Bibliographic Details
Main Authors: Chen, Wei, Xia, Yanping, Zhao, Xuelan, Wang, Hao, Chen, Wenjie, Yu, Maohua, Li, Yiming, Ye, Hongying, Zhang, Yu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462191/
https://ncbi.nlm.nih.gov/pubmed/23049681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045541
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items