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Human rotavirus vaccine Rotarix™ provides protection against diverse circulating rotavirus strains in African infants: a randomized controlled trial

BACKGROUND: Rotaviruses are the most important cause of severe acute gastroenteritis worldwide in children <5 years of age. The human, G1P[8] rotavirus vaccine Rotarix™ significantly reduced severe rotavirus gastroenteritis episodes in a Phase III clinical trial conducted in infants in South Afri...

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Main Authors: Steele, Andrew Duncan, Neuzil, Kathleen M, Cunliffe, Nigel A, Madhi, Shabir A, Bos, Pieter, Ngwira, Bagrey, Witte, Desiree, Todd, Stacy, Louw, Cheryl, Kirsten, Mari, Aspinall, Sanet, Van Doorn, Leen Jan, Bouckenooghe, Alain, Suryakiran, Pemmaraju V, Han, Htay Htay
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462149/
https://ncbi.nlm.nih.gov/pubmed/22974466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-213
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