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The physiological significance of β-actin mRNA localization in determining cell polarity and directional motility

β-actin mRNA is localized near the leading edge in several cell types, where actin polymerization is actively promoting forward protrusion. The localization of the β-actin mRNA near the leading edge is facilitated by a short sequence in the 3′ untranslated region, the “zip code.” Localization of the...

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Autores principales: Shestakova, Elena A., Singer, Robert H., Condeelis, John
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC34620/
https://ncbi.nlm.nih.gov/pubmed/11416185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121146098
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