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Ketamine Decreases Resting State Functional Network Connectivity in Healthy Subjects: Implications for Antidepressant Drug Action

Increasing preclinical and clinical evidence underscores the strong and rapid antidepressant properties of the glutamate-modulating NMDA receptor antagonist ketamine. Targeting the glutamatergic system might thus provide a novel molecular strategy for antidepressant treatment. Since glutamate is the...

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Autors principals: Scheidegger, Milan, Walter, Martin, Lehmann, Mick, Metzger, Coraline, Grimm, Simone, Boeker, Heinz, Boesiger, Peter, Henning, Anke, Seifritz, Erich
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461985/
https://ncbi.nlm.nih.gov/pubmed/23049758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044799
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